Molecular Neuropharmacology: A Foundation for Clinical Neuroscience, Second Edition

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Edition: 2nd
Format: Paperback
Pub. Date: 2008-11-17
Publisher(s): McGraw-Hill Professional
List Price: $71.00

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Summary

Turn to the classic primer of molecular neuroscience for a complete understanding of nervous system function and it's relationship to human neurologic disordersMolecular Neuropharmacologyoffers a clear, thorough explanation of the molecular functioning of the nervous system in normal and disease states. More than three hundred concept-clarifying full-color illustrations along with didactic text boxes provide an in-depth understanding of nerve cell receptors, their effectors and second messenger targets, and the molecular genetics that are often impacted by these systems. You will also learn how malfunction of these molecular systems relates to human disease and the corresponding medical treatment.Molecular Neuropharmacologyis the most relevant, well-written resource available to help you make the connection between neuropharmacology and clinical neuroscience.FEATURES: Numerous figures and didactic boxes to help you understand and remember complex subject matter for efficient, on-the-spot review All-inclusive, high-yield coverage, including: The fundamentals of neuropharmacology Neural substrates of drug action The neuorpharmacology of specific functions and disorders-encompassing control of movement, mood and emotion, memory and dementia, and other vital areas NEW! A streamlined redesign that makes the book even more practical and accessible than ever NEW! More illustrations-all 300 now in full color!

Author Biography

Eric J. Nestler, MD, is professor and chairman of the Department of Psychiatry and the Center for Basic Neuroscience at the Southwestern Medical School, Graduate School of Biomedical Science in Dallas, Texas.

Stephen E. Hyman, MD, is provost of Harvard University and professor of neurobiology at Harvard Medical School.

Robert C. Malenka, MD, Ph.D., is Pritzker Professor of Psychiatry & Behavioral Sciences at Stanford University.

Table of Contents

Contributing Authors to the Second Editionp. ix
Contributing Authors to the First Editionp. xi
Prefacep. xiii
Fundamentals of Neuropharmacology
Basic Principles of Neuropharmacologyp. 3
Cellular Basis of Communicationp. 16
Synaptic Transmissionp. 55
Signal Transduction in the Brainp. 74
Neural Substrates of Drug Action
Excitatory and Inhibitory Amino Acidsp. 117
Widely Projecting Systems: Monoamines, Acetylcholine, and Orexinp. 145
Neuropeptidesp. 181
Atypical Neurotransmittersp. 199
Neuropharmacology of Neural Systems and Disorders
Autonomic Nervous Systemp. 227
Neural and Neuroendocrine Control of the Internal Milieup. 246
Pain and Inflammationp. 269
Sleep and Arousalp. 289
Higher Cognitive Function and Behavioral Controlp. 313
Mood and Emotionp. 335
Reinforcement and Addictive Disordersp. 364
Schizophrenia and Other Psychosesp. 389
Neurodegenerationp. 409
Seizure Disordersp. 443
Stroke and Migrainep. 457
Indexp. 475
Table of Contents provided by Ingram. All Rights Reserved.

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