GI Epidemiology Diseases and Clinical Methodology

The only book to combine epidemiological analysis of gastrointestinal diseases with an examination of the methodologies of clinical research, GI Epidemiology, 2nd Edition, unites global experts to identify why and how GI diseases occur, to whom, and what can be done to prevent them. With new editors, new contributors, and a new, more user-friendly approach to epidemiology, this edition presents vital information in an accessible framework.

Nicholas J. Talley, University of Newcastle, Callaghan, NSW, Australia

G. Richard Locke III, Division of Gastroenterology and Hepatology, Mayo Clinic College of Medicine,
Rochester, MN, USA

Paul Moayyedi, McMaster University, Hamilton, ON, Canada

Joe West, Leeds Teaching Hospital Trust, University of Nottingham, Nottingham, UK

Alexander C. Ford, Leeds General Infirmary, Leeds, UK

Yuri A. Saito, Division of Gastroenterology and Hepatology, Mayo Clinic College of Medicine, Rochester, MN, USA

Contributors

Foreword

Preface

Part 1: Gastrointestinal Diseases and Disorders: The Public Health Perspective 

1 The Burden of Gastrointestinal and Liver Disease Around the World
Hannah P. Kim, Seth D. Crockett, Nicholas J. Shaheen

Part 2: How to Critically Read the Gastrointestinal Epidemiology Literature

Introduction and Overview
Joe West

2 How to Read a Cohort Study
Laila J. Tata
 
3 How to Read a Case-Control Study
Joe West, Laila J. Tata, Timothy R. Card

4 How to Read a Randomised Controlled Clinical Trial
Matthew J. Grainge

5 How to Read a Systematic Review and Meta-analysis
Alexander C. Ford, Paul Moayyedi

6 How to Decide if Any of This Matters
Kate M. Fleming, Timothy R. Card

Part 3: How to Do Clinical Research in GI

7 How to Develop and Validate a GI Questionnaire
G. Richard Locke, Enrique Rey

8 How to Do Population-Based Studies and Survey Research
Sanjiv Mahadeva, Hematram Yadav

9 How to Find and Apply Large Databases for Epidemiological Research
Jonas F. Ludvigsson, Joe West, Jessica A. Davila, Timothy R Card and Hashem B. El-Serag

10 How to Do Genetic and Molecular Epidemiological Research
Yuri A. Saito

11 Diagnostic Studies
Paul Moayyedi

12 Randomized Control Trials
Paul Moayyedi, Richard H. Hunt

Part 4: Epidemiology of Major GI Diseases
 
13 Epidemiology of GERD, Barrett's Esophagus and Esophageal Cancer
David Armstrong

14 Epidemiology of Helicobacter pylori Infection, Peptic Ulcer Disease and Gastric Cancer
Grigorios I. Leontiadis, Olof Nyrén

15 Epidemiology of Dyspepsia
Alexander C. Ford, Nicholas J. Talley

16 Epidemiology of Upper Gastrointestinal Bleeding
Colin J. Crooks, Joseph Sung, Timothy R. Card

17 Epidemiology of Celiac Disease
Alberto Rubio-Tapia, Jonas F. Ludvigsson, Joseph A. Murray

18 Measuring Utilization of Endoscopy in Clinical Practice
Frances Tse, Alan Barkun

19 Epidemiology of Colorectal Carcinoma
Harminder Singh, Joselito M. Montalban, Salaheddin Mahmud

20 Epidemiology of Irritable Bowel Syndrome
Rok Seon Choung, Yuri A. Saito

21 Epidemiology of Constipation
Brian E. Lacy, John M. Levenick

22 Epidemiology of Diverticular Disease
Robin Spiller, David Humes

23 Epidemiology of Infectious Diarrhea
Christina M. Surawicz, Crenguta Stepan

24 Epidemiology of Inflammatory Bowel Disease
Edward V. Loftus, Jr.

25 Epidemiology of Fecal Incontinence
Adil E. Bharucha

26 Epidemiology of Gallstones and Biliary Tract Cancers
Guy D. Eslick, Eldon A. Shaffer

27 Epidemiology of Pancreatitis
Dhiraj Yadav, Santhi Swaroop Vege, Suresh T. Chari

28 Epidemiology of Pancreatic Cancer
Aravind Sugumar, Santhi Swaroop Vege

29 Epidemiology of Hepatitis B and C in the United States
Sumeet K. Asrani, W. Ray Kim

30 Epidemiology of Alcoholic Liver Disease
Sumeet K. Asrani, William Sanchez

31 Epidemiology of Cirrhosis and Hepatocellular Carcinoma
Joe West, Guruprasad P. Aithal

32 Epidemiology of Nonalcoholic Fatty Liver Disease (NAFLD)
Guruprasad P. Aithal, Kshaunish Das, Abhijit Chowdhury

33 Epidemiology of Common Tropical GI Diseases
Magnus Halland, Rod Givney, Anne Duggan

34 Nutritional Epidemiology and GI Cancers
Linda E. Kelemen, Ilona Csizmadi

35 The Epidemiology of Obesity Among Adults
Cynthia L. Ogden, Brian K. Kit, Tala H.I. Fakhouri, Margaret Carroll, Katherine M. Flegal

Index

ADDITIONAL CHAPTERS: AVAILABLE ONLINE 
 
Part 1: Gastrointestinal Disease and Disorders: The Public Health Perspective
 
1 The Importance of GI Epidemiology
G. Richard Locke, Nicholas J. Talley

Part 2: Methodological Issues in GI Epidemiology
 
2 Overview of Epidemiologic Methodology
L. Joseph Melton III

3 Patient-reported Outcomes
Ingela Wiklund

4 Clinical Trials
William J. Sandborn

5 Decision Analysis
John M. Inadomi

6 Health Economics
Dawn Provenzale, Joseph Lipscomb

7 Systematic Reviews
Philip Schoenfield

8 Meta-analyses
Paul Moayyedi

9 A Career in GI Epidemiology
Linda Rabeneck

10 Funding Opportunities at the National Institutes of Health
James E. Everhart, Judith M. Podskalny