Frontiers in Celiac Disease
by Fasano, A.Edition: 1st
Format: Hardcover
Pub. Date: 2008-05-01
Publisher(s): KARGER, S. PUBLISHERS INC
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Summary
Few other fields in human biology have experienced such a tremendous progress as celiac disease has during the past few years. The contributors to 'Frontiers in Celiac Disease' are world-renowned opinion leaders who made these advances possible. Their expertise has been assembled here to provide a comprehensive overview of the current knowledge of the epidemiology, pathogenesis, clinical presentations, diagnosis and treatment of celiac disease. In addition, the stage is set for innovative strategies for preventive interventions and treatment alternatives to a gluten-free diet. A valuable reference for basic and translational scientists, this book also serves as a practical resource to healthcare professionals, including general practitioners, subspecialists, dieticians, nutritionists, and nurses and nurse practitioners. Students from different disciplines will find this book a helpful guide to expand and deepen their knowledge of celiac disease.
Table of Contents
| Preface | |
| Historical Perspective of Celiac Disease | p. 1 |
| Natural History of Celiac Disease | p. 12 |
| The Changing Clinical Presentation of Celiac Disease | p. 18 |
| The Global Village of Celiac Disease | p. 23 |
| HLA and Non-HLA Genes in Celiac Disease | p. 32 |
| Twins and Family Contribution to Genetics of Celiac Disease | p. 46 |
| Biochemistry and Biological Properties of Gliadin Peptides | p. 57 |
| Innate Immunity and Celiac Disease | p. 66 |
| Celiac Disease: Across the Threshold of Tolerance | p. 82 |
| The Role of the Intestinal Barrier Function in the Pathogenesis of Celiac Disease | p. 89 |
| Diagnosis of Coeliac Disease. Open Questions | p. 99 |
| Current Guidelines for the Diagnosis and Treatment of Celiac Disease | p. 107 |
| Current Therapy | p. 114 |
| Update on the Management of Refractory Coeliac Disease | p. 123 |
| The National Institutes of Health Consensus Conference Report | p. 133 |
| Beyond Coeliac Disease Toxicity. Detoxified and Non-Toxic Grains | p. 139 |
| Oral Glutenase Therapy for Celiac Sprue | p. 148 |
| Inhibitors of Intestinal Barrier Dysfunction | p. 157 |
| Development of a Vaccine for Celiac Disease | p. 172 |
| Regulatory T Cells in the Coeliac Intestinal Mucosa. A New Perspective for Treatment? | p. 181 |
| Strategies for Prevention of Celiac Disease | p. 188 |
| Towards Preventing Celiac Disease - An Epidemiological Approach | p. 198 |
| Animal Models of Celiac Disease | p. 210 |
| Author Index | p. 217 |
| Subject Index | p. 218 |
| Table of Contents provided by Blackwell. All Rights Reserved. |
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