Behavioral Genetics,9780716751595

Behavioral Genetics

by ; ; ;
Edition: 4th
ISBN13: 9780716751595
ISBN10: 0716751593
Format: Hardcover
Pub. Date: 2000-11-15
Publisher(s): Worth Publishers
List Price: $136.90

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Summary

Behavioral Genetics,Fourth Editionprovides an engaging and clear overview of human and animal behavioral genetics that is designed to introduce students in the behavioral, biological, and social sciences to the field. With the addition of new chapters, thorough updating, and a new co-author, this latest edition represents the definitive introduction to behavioral genetics: the crossroads where the fields of psychology, psychiatry, and genetics intersect.

Author Biography

Robert Plomin is professor of behavioral genetics at the Institute of Psychiatry in London John C. DeFries is professor of psychology University of Colorado, Boulder Gerald E. McClearn is Evan Pugh Professor in the at Pennsylvania State University, University Park Peter McGuffin is director of the Medical Research Council (UK) Social, Genetic and Developmental Psychiatry Research Centre at the Institute of Psychiatry, Kings College, London

Table of Contents

About the Authors xv
Preface xvii
Overview
1(5)
Mendel's Laws of Heredity
6(14)
Mendel's First Law of Heredity
7(7)
Huntington's Disease
8(1)
Phenylketonuria
9(1)
Gregor Mendel's Luck
10(3)
How Do We Know That 1 in 50 People Are Carriers for PKU?
13(1)
Mendel's Second Law of Heredity
14(4)
Summary
18(2)
Beyond Mendel's Laws
20(21)
Genes on the X Chromosome
20(3)
Other Exceptions to Mendel's Laws
23(5)
New Mutations
23(1)
Changes in Chromosomes
23(2)
Expanded Triplet Repeats
25(1)
Genomic Imprinting
26(2)
Complex Traits
28(5)
Schizophrenia
29(1)
General Cognitive Ability
30(1)
Pea Size
31(2)
Multiple-Gene Inheritance
33(2)
Quantitative Genetics
35(5)
Liability-Threshold Model of Disorders
38(2)
Summary
40(1)
DNA: The Basis of Heredity
41(20)
DNA
41(6)
The ``Central Dogma'' of Molecular Genetics
44(3)
Gene Regulation
47(2)
Mutations
49(2)
Detecting Polymorphisms
51(4)
DNA Markers
52(3)
Chromosomes
55(4)
Summary
59(2)
Nature, Nurture, and Behavior
61(32)
Genetic Experiments to Investigate Animal Behavior
62(10)
Selection Studies
65(3)
Inbred Strain Studies
68(4)
Investigating the Genetics of Human Behavior
72(13)
Adoption Designs
72(1)
Close-Up
73(2)
Lindon Eaves
Twin Design
75(1)
The First Adoption Study of Schizophrenia
76(2)
Issues in Adoption Studies
78(2)
Close-Up
80(1)
Nancy Pedersen
The Twin Method
81(1)
Combination Designs
82(1)
Close-Up
83(2)
Nick Martin
Heritability
85(8)
Interpreting Heritability
87(4)
Equality
91(1)
Summary
92(1)
Identifying Genes
93(23)
Animal Behavior
94(9)
Induced Mutations
95(3)
Quantitative Trait Loci
98(1)
Close-Up
99(4)
Jonathan Flint
Synteny Homology
103(1)
Human Behavior
103(10)
Linkage
105(1)
Association
106(1)
Close-Up
106(1)
Peter Propping
Affected Sib-Pair Linkage Design
107(1)
Within-Family Tests of Association
108(3)
Genetic Counseling
111(1)
GATTACA?
112(1)
Ethics and the Future
113(1)
Summary
113(3)
Neurogenetics
116(16)
Induced Mutations
116(2)
Circadian Rhythms
118(2)
Learning and Memory
120(2)
Close-Up
122(1)
Tim Tully
Targeted Mutations
122(4)
Close-Up
124(2)
Jeanne Wehner
Antisense DNA
126(1)
``Chips'' for DNA Expression
127(1)
Naturally Occurring Genetic Variation
127(1)
Functional Genomics
128(2)
Human Neurogenetics
130(1)
Summary
130(2)
Cognitive Disabilities
132(24)
Mental Retardation: Quantitative Genetics
133(2)
Mental Retardation: Single-Gene Disorders
135(3)
Phenylketonuria
135(1)
Fragile X Syndrome
136(2)
Rett Syndrome
138(1)
Other Single-Gene Disorders
138(3)
Duchenne Muscular Dystrophy
138(1)
Lesch-Nyhan Syndrome
138(1)
Neurofibromatosis Type 1 (NF1)
139(2)
Mental Retardation: Chromosomal Abnormalities
141(4)
Down Syndrome
142(1)
Sex Chromosome Abnormalities
143(2)
Learning Disorders
145(3)
Close-Up
148(1)
Shelley Smith
Communication Disorders
148(1)
Dementia
149(5)
DF Extremes Analysis
150(4)
Summary
154(2)
General Cognitive Ability
156(28)
Historical Highlights
158(8)
Animal Research
159(3)
Francis Galton
162(2)
Human Research
164(2)
Overview of Genetic Research
166(7)
Genetic Influence
166(1)
Close-Up
167(2)
Thomas J. Bouchard, Jr.
Environmental Influence
169(1)
Assortative Mating
169(1)
Nonadditive Genetic Variance
170(3)
Developmental Research
173(6)
Does Heritability Change During Development?
173(4)
Do Genetic Factors Contribute to Developmental Change?
177(2)
Identifying Genes
179(3)
Summary
182(2)
Specific Cognitive Abilities
184(20)
Broad Factors of Specific Cognitive Abilities
184(8)
Close-Up
192(1)
Stephen A. Petrill
Information-Processing Measures
192(3)
Multivariate Genetic Analysis: Levels of Processing
195(3)
School Achievement
198(3)
Close-Up
199(2)
Juko Ando
Identifying Genes
201(1)
Summary
202(2)
Psychopathology
204(30)
Schizophrenia
204(13)
Family Studies
205(1)
The Beginnings of Psychiatric Genetics
206(2)
Close-Up
208(1)
Irving I. Gottesman
Twin Studies
209(1)
Adoption Studies
210(3)
Schizophrenia or Schizophrenias?
213(1)
Close-Up
214(1)
Kenneth S. Kendler
Identifying Genes
215(2)
Mood Disorders
217(5)
Family Studies
217(2)
Twin Studies
219(1)
Adoption Studies
220(1)
Identifying Genes
221(1)
Anxiety Disorders
222(2)
Other Disorders
224(2)
Disorders of Childhood
226(4)
Autism
226(1)
Attention-Deficit and Disruptive Behavior Disorders
227(1)
Close-Up
228(1)
Anita Thapar
Other Disorders
229(1)
Co-Occurrence of Disorders
230(2)
Summary
232(2)
Personality and Personality Disorders
234(24)
Self-Report Questionnaires
235(3)
Other Measures of Personality
238(3)
Close-Up
240(1)
Rainer Riemann
Other Findings
241(3)
Situations
241(1)
Development
242(1)
Nature-Nurture Interplay
242(1)
Close-Up
243(1)
Hill Goldsmith
Personality and Social Psychology
244(4)
Relationships
244(1)
Close-Up
245(1)
Michael Bailey
Self-Esteem
246(1)
Attitudes and Interests
246(2)
Personality Disorders
248(2)
Antisocial Personality Disorder and Criminal Behavior
250(4)
Identifying Genes
254(2)
Summary
256(2)
Health Psychology and Aging
258(21)
Health Psychology
258(15)
Close-Up
259(1)
John K. Hewitt
Body Weight and Obesity
259(2)
Close-Up
261(3)
Dorret Boomsma
Addictions
264(1)
Close-Up
265(5)
Matt McGue
Close-Up
270(3)
John Crabbe
Stress and Cardiovascular Risk
273(1)
Psychology and Aging
274(3)
Summary
277(2)
Evolution
279(17)
Charles Darwin
279(6)
Population Genetics
285(2)
Evolutionary Psychology
287(7)
Close-Up
290(2)
David M. Buss
Survival of the Prettiest?
292(2)
Summary
294(2)
Environment
296(23)
Nonshared Environment
297(9)
The Nurture Assumption
298(2)
Estimating Nonshared Environment
300(1)
Identifying Specific Nonshared Environment
301(2)
Identifying Specific Nonshared Environment That Predicts Psychology Outcomes
303(1)
Implications
304(2)
Genotype-Environment Correlation
306(8)
The Nature of Nurture
306(1)
Close-Up
307(2)
David Rowe
Three Types of Genotype-Environment Correlation
309(1)
Three Methods to Detect Genotype-Environment Correlation
310(3)
Implications
313(1)
Genotype-Environment Interaction
314(3)
Identifying Genes for Experience
317(1)
Summary
317(2)
Behavioral Genetics in the Twenty-first Century
319(8)
Quantitative Genetics
319(3)
Molecular Genetics
322(1)
Nature and Nurture
323(4)
APPENDIX Statistical Methods in Behavioral Genetics 327(46)
Box A. 1 Behavioral Genetic Interactive Modules
328(1)
Close-Up
329(1)
Shaun Purcell
Variance
329(4)
Individual Differences
329(1)
Populations and Samples
329(1)
Descriptive Statistics
330(1)
The Mean
330(1)
Variance
331(1)
Standardized Scores
332(1)
Covariance
333(4)
Variance of a Sum
337(1)
Correlation and Regression
337(2)
Matrices
339(3)
A Single-Gene Model
342(3)
Alleles and Genotypes
342(1)
Genotypic Values
343(1)
Additive Effects
343(1)
Dominance Deviation
343(2)
Polygenic Model
345(1)
Phenotypic Values and Variance Components Model
345(2)
Environmental Variation
346(1)
Families
347(4)
Genetic Relatedness in Families
348(1)
Heritability
349(2)
Model Fitting
351(8)
Model Fitting on Twin Data
352(2)
An Example
354(1)
A Problem!
355(1)
ACE Model
356(3)
Path Analysis
359(2)
Multivariate Analysis
361(5)
Complex Effects
366(2)
Extremes Analysis
368(1)
Mapping Quantitative Trait Loci
369(4)
Linkage and Association
369(1)
Variance components Model of Linkage
369(2)
QTL Association in Families
371(2)
Glossary 373(8)
References 381(52)
Web Sites 433(2)
Name Index 435(10)
Subject Index 445

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