Alternatives to Blood Transfusion in Transfusion Medicine
by Maniatis, Alice; Hardy, Jean-Franç; ois; van der Linden, PhillipeEdition: 2nd
Format: Hardcover
Pub. Date: 2010-11-08
Publisher(s): Wiley-Blackwell
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Summary
Meeting the needs of patients while minimizing blood transfusions requires special expertise, precise monitoring and innovative techniques. This cutting-edge resource covers all the important clinical aspects of transfusion medicine in diverse clinical settings, with a special emphasis on alternatives to transfusion.Edited by a multidisciplinary team consisting of a transfusion specialist, an anesthesiologist and an intensive care specialist this book is endorsed by the Network for Advancement of Transfusion Alternatives. The contributors review the appropriate use of fluids and of blood products, and describe the latest treatment options available to decrease the need for allogeneic blood products including: Argon beam Cell saver Harmonic scalpel Normovolemic haemodilution Synthetic erythropoietin Antifibrinolytics Recombinant factor VIIa Advanced monitoring of hemostasis Intravenous ironThe new edition is a key reference source for all those involved in the practice of blood management and conservation.
Author Biography
Professor Alice Maniatis, Haematology Department of Internal Medicine, University of Greece, Athens, Greece and former President of Network for Advancement of Transfusion Alternatives (NATA).
Dr Jean-Francois Hardy, Department of Anesthesia, Montreal Heart Institute, Quebec, Canada and on the Board of Directors of NATA.
Dr Phillipe van der Linden, Department of Anesthesiology and Intensive Care, Brussels, Belguim and on the Board of Directors of NATA.
Table of Contents
| List of Contributors | |
| Preface | |
| History and Development of Transfusion Medicine | |
| From blood transfusion to transfusion medicine | |
| Allogeneic Blood Usage -- Risks and Benefits | |
| Allogeneic Blood Components | |
| Current Information on the Infectious Risks of Allogeneic Blood Transfusion | |
| Immunological Complications of Transfusion | |
| Immunomodulation and Allogeneic Transfusion | |
| Pathogen Inactivation (of Blood Components) | |
| The Benefits of Allogeneic Erythrocyte Transfusion: What Evidence Do We Have? | |
| Volume Replacement | |
| Plasma and Albumin | |
| Plasma and Albumin | |
| Crystalloids and Synthetic Colloids | |
| Pharmacology of Intravenous Fluids | |
| Crystalloids Versus Colloids: The Controversy | |
| Effects of Synthetic Colloids on Hemostasis | |
| Hydroxyethyl starch and renal dysfunction | |
| Choice of a Synthetic Colloid for Surgery | |
| Choice of a Colloid for Intensive Care Patients | |
| Hypertonic Saline Solutions for the Initial Treatment of Patients with Traumatic Injuries | |
| Hyperchloremic Acidosis | |
| Tolerance of Anemia | |
| Basic Principles of Oxygen Transport and Calculations | |
| Assessment of Tissue Oxygenation | |
| Tissue Oxygenation and Blood Transfusion | |
| Anemia and Cardiovascular Disease | |
| Perioperative Hemostasis | |
| Monitoring of Hemostasis in the Perioperative Setting | |
| Antifibrinolytics in open heart surgery | |
| Efficacy and Safety of Recombinant Activated Factor VII to Control Bleeding in Non-hemophiliac Patients | |
| Transfusion Triggers | |
| Role of Hemoglobin/Hematocrit | |
| Calculation of Blood Loss | |
| Management of massive transfusion | |
| Alternatives to Allogeneic Blood Transfusion | |
| Pharmaceutical Approaches | |
| Iron deficiency: causes, diagnosis and management | |
| Current Status of Perisurgical Erythropoietin Therapy | |
| Erythropoietin and Iron Therapy in Patients with Renal Failure | |
| Hemoglobin-Based Blood Substitutes | |
| Perfluorocarbon Emulsions | |
| Surgical Techniques | |
| Minimally Invasive Cardiac Surgery: Impact on Blood Loss and Transfusion | |
| Adjunctive Strategies to Impact Blood Transfusion in Cardiac Surgery | |
| Anesthetic Techniques | |
| Anesthetic Techniques to Reduce Blood Loss | |
| Controlled Hypotension Decreases Blood Transfusion Requirement: Fact or Fallacy? | |
| Acute Normovolemic Hemodilution | |
| Hyperoxic Hemodilution | |
| Intraoperative and Postoperative Cell Salvage | |
| Special Settings | |
| Anemia and Red Blood Cell Transfusion in Critical Care | |
| Red Blood Cell Transfusions and Alternatives to Treat the Anemia of Prematurity | |
| Transfusion Alternatives in Orthopedic Surgery | |
| Transfusion Alternatives in Obstetrics | |
| Legal and Ethical Issues in Transfusion Medicine | |
| Ethical Aspects of Informed Consent: American Models | |
| Blood Transfusions, Jehovah's Witnesses and the American Patients' Rights Movement | |
| Cost Issues | |
| The Cost and Cost Effectiveness of Allogeneic and Autologous Blood | |
| Autologous Blood Predonation in Cardiac Surgery | |
| Cost-Effectiveness of Pharmacological Alternatives | |
| Table of Contents provided by Publisher. All Rights Reserved. |
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